WP 6.2Spoke 06

Reduce malnutrition: strategies in a sustainable framework

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Work Package 6.2 will present a sustainable, tailored, multidimensional approach to reducing malnutrition by exploiting the interactions between environment, food, genotype, and phenotype within specific population groups. 

As part of this work, it is also expected an analysis of the positive and negative interactions between lifestyle, socioeconomic status, clinical condition, psychological distress, medical treatment, and diet for the implementation of sustainable dietary patterns; a validation of biomarker malnutrition and a draft of sustainable nutritional protocols, in relation with Spoke 1 and 4.

The next task that will be carried out jointly with Spoke 2, 3 and 4 is centred on developing and applying in vitroin vivo, and in silico experimental models to understand better the mechanisms of action in counteracting malnutrition of new sustainable bioactive molecules from different matrices.

The final task of Work Package 6.2 relies on designing a user-friendly, personalised web tool for monitoring and fostering remotely sustainable, target-specific food behaviours. The application's responsiveness features will be available on various devices like PCs and smartphones.

Task and deliverables

Task 6.2.1.

Identification of sustainable tailored multidimensional approach including nutritional strategies aimed at reducing malnutrition in target specific populations by exploiting the interactions between environment, food, genotype and phenotype: a) analysis of the positive and negative interactions between lifestyle, socioeconomic status, clinical condition, psychological distress, medical treatment and diet for the implementation of sustainable dietary patterns; b) malnutrition biomarker validation; c) draft of sustainable nutritional protocols (in connection with Spoke 1 and 4).

Task 6.2.2.

Development and application of in vitro, in vivo and in silico experimental models for the understanding of the mechanism of action in counteracting malnutrition of new sustainable bioactive molecules from different matrices (in connection with Spoke 2, 3 and 4).

Task 6.2.3.

Design of a friendly end user personalised web responsive application for remote promoting and monitoring of sustainable target specific dietary patterns. The responsiveness features of the application will be made available on different devices (e.g., PC, smartphone)

Milestones

M6.2.1.1.

List of nutrition protocols and existing biomarkers for specific target groups with malnutrition that would benefit improvement (M12)

M6.2.2.1.

List of new sustainable bioactive molecules proven to directly impact nutritional status in specific target groups with malnutrition (M18)

M6.2.3.1.

Identification and computerization of existing Clinical Practice Guidelines addressing malnutrition (M8)

M6.2.3.2.

Development of an engine for assessing dietary regimens based on their observed efficacy on the target patients (M18).

Research projects

Research projectFACILITY

Feeding the family: the Intergenerational approach to fight obesity


Managed by


Principal investigators

Hellas Cena,Valeria Calcaterra

Referred to

Spoke 06
Research projectFOODS_MALT

New food supplements ingredients for malnutrition treatment


Managed by


Principal investigators

Luca Campone,Paola Coccetti,Sandra Citterio,Paola Noverina Palestini,Massimo Labra

Referred to

Spoke 06
Research projectGLUTTON

Tackling milk formula composition to improve infant nutrition


Managed by


Principal investigators

Antonio Dario Troise,Laura Cavallarin

Referred to

Spoke 06
Research projectIBD-ONFOODS

A Multidimensional Assessment for Tackling Malnutrition in Inflammatory Bowel Disease


Managed by


Principal investigators

Marco Vincenzo Lenti,Antonio Di Sabatino,Federica Lepore

Referred to

Spoke 06
Research projectMAD

Malnutrition in patients with immune-mediated diseases


Managed by


Principal investigators

Roberto Berni Canani,Lutgarda Bozzetto,Valentina Discepolo,Antonio Molinaro,Raffaele Capasso

Referred to

Spoke 06
Research projectNAOM

New therapeutic approach against obesity and metabolic diseases


Managed by


Principal investigators

Roberto Berni Canani,Lutgarda Bozzetto,Valentina Discepolo,Antonio Molinaro,Raffaele Capasso

Referred to

Spoke 06
Research projectNUTRIA

A mobile nutritional application for assessing patient risk and improving dietary habits


Managed by


Principal investigators

Giordano Lanzola

Referred to

Spoke 06
Research projectNUTRICEL

The impact of nutrition in the natural history of celiac disease


Managed by


Principal investigators

Valentina Discepolo,Roberto Berni Canani,Lutgarda Bozzetto,Antonio Molinaro,Raffaele Capasso

Referred to

Spoke 06

Referred to

Spoke 06
Research projectPREDICTABILITY

Predictive tool for cardio-metabolic risk in children with obesity


Managed by


Principal investigators

Valeria Calcaterra

Referred to

Spoke 06
Research projectSENIOR

Sustainable eating patterns to limit malnutrition in older adults


Managed by


Principal investigators

Hellas Cena,Flavia Magri,Antonio Di Sabatino

Referred to

Spoke 06
Research projectSIL_FOOD

Use of in silico models to tackle malnutrition


Principal investigators

Emilio Benfenati

Referred to

Spoke 06

Referred to

Spoke 06
Research projectTM-SO

Tackle malnutrition – focus on sarcopenic obesity


Managed by


Principal investigators

Lorenzo Maria Donini,Elisa Giannetta,Laura Masuelli,Alessio Molfino

Referred to

Spoke 06