Funded under the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.3, Theme 10.
Highlights
Spoke 05
A significant research focus concerned older adults, a population group particularly exposed to subtle yet clinically relevant forms of malnutrition. Nutritional adequacy was analysed across different living contexts, including community and residential settings, examining dietary habits, health conditions, lifestyle patterns and service organisation. Existing nutritional protocols were compared and critically evaluated, highlighting the need for greater harmonisation and improved awareness among older individuals and their caregivers.
The research also investigated energy and protein requirements in adulthood and ageing, critically assessing the validity of predictive equations used to estimate resting energy expenditure. Commonly applied formulas were compared with reference methods based on more precise metabolic and functional measurements. The findings clarified the strengths and limitations of current approaches and emphasised the importance of more accurate estimations to support genuinely personalised nutritional recommendations, particularly for older and physically active populations. In parallel, the role of protein intake in preventing functional decline was explored, including the evaluation of alternative and unconventional protein sources in relation to nutritional needs and sustainability.
Special attention was dedicated to early life stages, recognised as critical windows for chronic disease prevention. Observational studies and lifestyle interventions deepened the understanding of maternal, nutritional and environmental determinants during pregnancy and the first 1,000 days of life. The establishment of prospective cohorts and longitudinal data collection strengthened the scientific basis for primary prevention strategies focused on dietary quality, gestational weight management and early metabolic health.
The analysis was extended to adult populations with specific nutritional requirements, including physically active individuals and young adults. Original data on dietary patterns, physical activity, sleep quality and nutritional knowledge contributed to the development and validation of targeted assessment tools. Evidence-based educational interventions demonstrated that structured approaches can enhance adherence to healthy and sustainable dietary models, even in socially diverse and highly mobile contexts.
In addition to generating original data, WP 5.2 played a relevant role in reviewing and harmonising existing guidelines and position papers. The adopted framework integrated nutritional factors, lifestyle behaviours, intra- and inter-individual variability and environmental exposures, reinforcing the scientific foundations for life-course nutrition strategies.
Verify the adequacy of nutrition in the elderly. Investigation on specific elements of risk on elderly nutrition starting collaboration with senior membership circles (i.e., church circles, sport circles) and elderly care homes.
Assessment of energy requirements in adults and elderly and evaluation of the validity of different predictive equations used to estimate resting energy expenditure vs. a gold standard (wearable metabolic technology, indirect calorimetry combined with accelerometry) in adults and elderly population.
Definition of protein requirements changes with advancing age (in adults and elderly subjects) and analysis of nutritional characteristics of unconventional protein sources (e.g., grains, pseudo-grains, pulses, algae, fungi) in connection with Spoke 3, 4 and 6.
Collection and harmonisation of existing guidelines and position papers taking into consideration the nutritional and lifestyle aspects as well as the intra/inter-individual variables and the environmental exposures affecting health promotion across life stages, with attention to maternal-infant dyad in the "first 1000 days", adult population (including physically active people and athletes) and free-living older adults.
Definition of new protocols/surveys for the evaluation of the nutritional status across life stages, with attention to maternal-infant dyad in the "first 1000 days"; b) adult population (including physically active people and athletes); and free-living older adults.
Education and training at different levels for i) academic; ii) healthcare professionals; iii) industries; iv) general population to promote models for healthy nutritional schemes (in connection with Spoke 7).
Identification of cohort studies (M6)
Acquisition of Italian policies, services, and good practices for health promotion during lifespan (milestone shared with spoke 7) (M18)