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Association between Late-Eating Pattern and Higher Consumption of Ultra-Processed Food among Italian Adults: Findings from the INHES Study

Bonaccio, M., Ruggiero, E., Di Castelnuovo, A., Martínez, C. F., Esposito, S., Costanzo, S., Cerletti, C., Donati, M. B., De Gaetano, G., Iacoviello, L.; INHES Study Investigators.

Nutrients. 2023 Mar 20;15(6):1497

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March 20, 2023


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Late eating is reportedly associated with adverse metabolic health, possibly through poor diet quality. We tested the hypothesis that meal timing could also be linked to food processing, an independent predictor of health outcomes. We analysed data on 8688 Italians (aged > 19years) from the Italian Nutrition & HEalth Survey (INHES) established in 2010–2013 throughout Italy. Dietary data were collected through a single 24 h dietary recall, and the NOVA classification was used to categorize foods according to increasing levels of processing: (1) minimally processed foods (e.g., fruits); (2) culinary ingredients (e.g., butter); (3) processed foods (e.g., canned fish); (4) ultra-processed foods (UPFs; e.g., carbonated drinks, processed meat). We then calculated the proportion (%) of each NOVA group on the total weight of food eaten (g/d) by creating a weight ratio. Subjects were classified as early or late eaters based on the population’s median timing for breakfast, lunch and dinner. In multivariable-adjusted regression models, late eaters reported a lower intake of minimally processed food (β = −1.23; 95% CI −1.75 to −0.71), a higher intake of UPF (β = 0.93; 0.60 to 1.25) and reduced adherence to a Mediterranean Diet (β = −0.07; −0.12 to −0.03) as compared to early eaters. Future studies are warranted to examine whether increased UPF consumption may underpin the associations of late eating with adverse metabolic health reported in prior cohorts.

This research output is related to

Spoke 05

Lifelong nutrition

A healthy diet for all

Lead organisationUniNa

Spoke leaderAnnamaria Colao
Research projectPROMETEO

Promoting adherence to an unprocessed mediterranean diet over the lifecourse


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Principal investigators

Licia Iacoviello,Marialaura Bonaccio

Referred to

Spoke 05